September 7-9, 2015
This course provides exhaustive knowledge in the principles and practice of Diagnostic tests to comprehend reliability and validity of a new diagnostic test, the biases and the challenges in designing a study and, critically evaluate a diagnostic study article. This course will also cover the basics of quality control methods in a laboratory. This course will include lectures and comprise a series of practical.
- Correctly interpret diagnostic information (sensitivity, specificity, likelihood ratios, ROCs, accuracy) from different data sources.
- Combine diagnostic information from multiple tests, when tests are independent and not independent.
- Expose common myths about diagnostic tests.
- Accurately interpret an ROC curve and identify best cutpoints.
- Recognize when verification bias (work-up bias) is a threat to study validity and calculate the magnitude of error from such bias.
- Assess magnitude and direction of error when the gold standard is imperfect.
- Generate likelihood ratios from logistic regression models, and understand relationship between odds ratios and likelihood ratios.
- Critique and revise published articles on diagnostic tests; optimize presentation of results.
Who should apply?
This course is tailored to medical, allied health professionals, nonmedical faculty, and/or researchers actively involved in diagnostic test research (validity and reliability studies), or teaching institution or in furthering their knowledge and skills in methodology.
- Each participant will be randomly allocated to a group and the group will be assigned a research question and given background materials to develop a protocol following STARD guidelines. Each group’s protocol development process will be facilitated by a mentor. Each group will be asked to present their protocol orally to the rest of the groups and faculty for discussion.
- Course kit will be provided.
Course Fee: Rs 5,000/ per person
(Course kit, Lunch, snacks and tea will be provided)
Course Fee should be paid in full by August 29, 2015. Payment can be made by Demand Draft (DD) in favour of “Christian Medical College Vellore Association Account “, payable at Vellore.
Participants will have to bear their own expenses for travel, boarding and lodging. The Organizers will provide Lunch and Snacks. However, the organizers may arrange basic accommodation with A/C facility in the college campus on request. Only limited accommodation is available on campus and priority will be given to the female participants.
nMaster (Sample Size calculation software)
cost of the nMaster software is fixed for Rs.2500/- for Academic /
Government institutions and Rs.5000/- for Commercial. However, those
who would participate in this workshop from the Academic / Government
institutions, a concession of Rs.1000/- will be offered to buy this
nMaster software (price - Rs.1500/-).
Biostatistics Resource and Training Centre (BRTC),
Department of Biostatistics,
Christian Medical College,
Vellore - 632 002.
The number of participants: Limited to 45 admissions & this will be purely on first come first served basis.